Interethnic differences in population prevalence of the HLA-B*1502 allele are shown below.
These data are crucial in preventing carbamazepine-induced Stevens-Johnson Symdrome and Toxic Epidermal Necrolysis.
Patients with HLA-B*1502 alleles face a highly increased risk of developing Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in response to carbamazepine treatment (Leckband et al. 2013).
In the map below data from the allelefrequencies.net are presented.
Color scheme:
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no data available |
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prevalence below 1 % *) |
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prevalence between 1 and 5 % *) |
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prevalence above 5 % *) |
*) Click country on map to view details
United Arab Emirates
United Arab Emirates pop 2 0.6% Sample size: 373
Afghanistan
Albania
Armenia
Angola
Argentina
Austria
Australia
| Australia Groote Eylandt Aborigine | 0.7% | Sample size: 75 |
| Australia New South Wales Caucasian | 0,00% | Sample size: 134 |
| Australia Yuendumu Aborigine | 0,00% | Sample size: 191 |
Azerbaijan
Bosnia and Herzegovina
Bangladesh
Belgium
Burkina Faso
Burkina Faso Fulani 0,00% Sample size: 49
Burkina Faso Rimaibe 0,00% Sample size: 47
Bulgaria
Bulgaria 0,00% Sample size: 55
Burundi
Benin
Brunei
Bolivia
Brazil
Brazil Belo Horizonte Caucasian 0,00% Sample size: 95
The Bahamas
Bhutan
Botswana
Belarus
Belize
Canada
Democratic Republic of the Congo
Central African Republic
Republic of the Congo
Switzerland
Ivory Coast
Chile
Cameroon
China
China Beijing 1.5% Sample size: 67
China Beijing pop 2 12.87% Sample size: 826
China Beijing Tianjian Han 2.4% Sample size: 618
China Canton Han 7.3% Sample size: 264
China Guangdong Meizhou Han 3.5% Sample size: 100
China Guangxi Region Maonan 14.8% Sample size: 108
China Guangzhou 11,00% Sample size: 102
China Guizhou Province Bouyei 15.5% Sample size: 109
China Guizhou Province Miao 4.2% Sample size: 85
China Guizhou Province Shui 15.6% Sample size: 153
China Han HIV negative 3.1% Sample size: 72
China Henan HIV negative 3.1% Sample size: 16
China Inner Mongolia Region 1.5% Sample size: 102
China Jiangsu Han 2.1% Sample size: 3,238
China Jiangsu Province Han 1.93% Sample size: 334
China North Han 1.9% Sample size: 105
China Qinghai Province Hui 2.7% Sample size: 110
China Sichuan HIV negative 1.5% Sample size: 34
China South Han 7.1% Sample size: 284
China Southwest Dai 6.9% Sample size: 124
China Tibet Region Tibetan 0,00% Sample size: 158
China Yunnan Bulang 35.8% Sample size: 116
China Yunnan Hani 10,00% Sample size: 150
China Yunnan Province Han 12.4% Sample size: 101
China Yunnan Province Jinuo 23.8% Sample size: 109
China Yunnan Province Lisu 12.3% Sample size: 111
China Yunnan Province Nu 9,00% Sample size: 107
China Yunnan Province Wa 21,00% Sample size: 119
Colombia
Costa Rica
Cuba
Cuba Caucasian 0,00% Sample size: 70
Cuba Mulatto 0,00% Sample size: 42
Cyprus
Czech Republic
Czech Republic 0,00% Sample size: 106
Czech Republic NMDR 0.01% Sample size: 5,099
Germany
Germany DKMS - China minority 3.3% Sample size: 1,282
Germany DKMS - Greece minority 0.03% Sample size: 1,894
Germany DKMS - Italy minority 0.04% Sample size: 1,159
Germany DKMS - Netherlands minority 0.11% Sample size: 1,374
Germany DKMS - Turkey minority 0.02% Sample size: 4,856
Germany pop 6 - (Caucasoid) 0.02% Sample size: 8,862
Germany pop 8 - (Caucasoid) 0.02% Sample size: 39,689
Djibouti
Denmark
Dominican Republic
Algeria
Ecuador
Estonia
Egypt
Western Sahara
Eritrea
Spain
Spain Andalusia Gipsy 1,00% Sample size: 99
Ethiopia
Finland
Fiji
Falkland Islands
France
Gabon
United Kingdom
Georgia
French Guiana
Ghana
Greenland
Gambia
Guinea
Equatorial Guinea
Greece
Greece pop 8 (Caucasoid) 0.6% Sample size: 83
Guatemala
Guinea Bissau
Guyana
Honduras
Croatia
Croatia 0,00% Sample size: 150
Haiti
Hungary
Indonesia
Indonesia Java pop 2 16.7% Sample size: 36
Indonesia Java Western 12.2% Sample size: 236
Indonesia Sundanese and Javanese 10.7% Sample size: 201
Ireland
Ireland Northern 0,00% Sample size: 1000
Israel
India
India Delhi pop 2 1.6% Sample size: 90
India Khandesh Region Pawra 6,00% Sample size: 50
India Mumbai Maratha 1.9% Sample size: 91
India North pop 2 1,00% Sample size: 72
India West Bhil 4,00% Sample size: 50
India West Coast Parsi 0,00% Sample size: 50
Iraq
Iran
Iran Gorgan 1.5% Sample size: 69
Iceland
Italy
Italy Bergamo 0,00% Sample size: 101
Italy South Campania Region 0.1% Sample size: 1,089
Jamaica
Jordan
Japan
Japan Central 0.1% Sample size: 371
Japan pop 16 0.03% Sample size: 18,604
Japan pop 3 0.1% Sample size: 1,018
Kenya
Kyrgyzstan
Cambodia
North Korea
South Korea
South Korea pop 10 0.33% Sample size: 4,128
South Korea pop 3 0.2% Sample size: 485
South Korea pop 8 2.2% Sample size: 7,096
Kuwait
Kazakhstan
Laos
Lebanon
Sri Lanka
Liberia
Lesotho
Lithuania
Luxembourg
Latvia
Libya
Morocco
Morocco Nador Metalsa pop 0,00% Sample size: 73
Morocco Settat Chaouya 0,00% Sample size: 98
Moldova
Montenegro
Madagascar
Macedonia
Mali
Myanmar
Myanmar Bamar 11.9% Sample size: 46
Myanmar Chin 28.18% Sample size: 55
Myanmar Kachin 19,00% Sample size: 63
Myanmar Kayah 15.45% Sample size: 55
Myanmar Kayin 23.9% Sample size: 44
Myanmar Mon 9.4% Sample size: 64
Myanmar Rakhine 14.58% Sample size: 48
Myanmar Shan 13.9% Sample size: 54
Mongolia
Mauritania
Malawi
Mexico
Mexico City Mestizo 0.8% Sample size: 121
Mexico City Mestizo pop 2 0.43% Sample size: 234
Mexico Mestizo 0,00% Sample size: 41
Mexico Puebla Mestizo 0.5% Sample size: 99
Mexico Sinaloa Mestizo 0,00% Sample size: 56
Malaysia
Malaysia Jelebu Temuan 6.3% Sample size: 25
Malaysia Pahang Semai 17.1% Sample size: 38
Malaysia Peninsular Chinese 5.67% Sample size: 194
Malaysia Peninsular Malay 12.25% Sample size: 951
Malaysia Perak Grik Jehai 2,00% Sample size: 25
Malaysia Sarawak Bau Bidayuh 16,00% Sample size: 25
Mozambique
Namibia
New Caledonia
Niger
Nigeria
Nicaragua
Netherlands
Netherlands Leiden 0,00% Sample size: 1,305
Norway
Nepal
New Zealand
Oman
Oman 0,00% Sample size: 118
Panama
Peru
Papua New Guinea
Philippines
Philippines Ivatan 22,00% Sample size: 50
Pakistan
Poland
Puerto Rico
West Bank
Portugal
Paraguay
Qatar
Romania
Romania 0,00% Sample size: 348
Republic of Serbia
Russia
Rwanda
Saudi Arabia
Solomon Islands
Sudan
Sudan Central Shaigiya Mixed 4.24% Sample size: 36
Sudan East Rashaida 1.86% Sample size: 27
Sweden
Slovenia
Slovakia
Sierra Leone
Senegal
Somalia
Suriname
South Sudan
El Salvador
Syria
Swaziland
Chad
French Southern and Antarctic Lands
Togo
Thailand
Thailand 8.5% Sample size: 142
Thailand Northeast pop 2 8.4% Sample size: 400
Thailand pop 3 8.2% Sample size: 49
Tajikistan
East Timor
Turkmenistan
Tunisia
Turkey
Trinidad and Tobago
Taiwan
Taiwan Ami 0,00% Sample size: 98
Taiwan Atayal 0,00% Sample size: 106
Taiwan Bunun 0,00% Sample size: 101
Taiwan Hakka 2.7% Sample size: 55
Taiwan Han Chinese 4.5% Sample size: 504
Taiwan Minnan pop 1 5.9% Sample size: 102
Taiwan Paiwan 0,00% Sample size: 51
Taiwan Pazeh 3.6% Sample size: 55
Taiwan pop 2 5.2% Sample size: 364
Taiwan pop 3 6,00% Sample size: 212
Taiwan Puyuma 18,00% Sample size: 50
Taiwan Rukai 0,00% Sample size: 50
Taiwan Saisiat 0,00% Sample size: 51
Taiwan Siraya 1,00% Sample size: 51
Taiwan Tao 12,00% Sample size: 50
Taiwan Taroko 0,00% Sample size: 55
Taiwan Thao 0,00% Sample size: 30
Taiwan Tsou 1,00% Sample size: 51
Taiwan Tzu Chi Cord Blood Bank 4.2% Sample size: 710
Tanzania
Ukraine
Uganda
United States of America
USA African American 0.2% Sample size: 252
USA African American Bethesda 0,00% Sample size: 187
USA African American pop 4 0.08% Sample size: 2,411
USA Alaska Yupik 0.2% Sample size: 252
USA Asian 4.9% Sample size: 358
USA Asian pop 2 3.57% Sample size: 1,772
USA Caucasian Bethesda 0,00% Sample size: 307
USA Caucasian pop 2 0,00% Sample size: 265
USA Hispanic 0,00% Sample size: 234
USA Hispanic pop 2 0.03% Sample size: 1,999
USA Mexican American Mestizo 0.1% Sample size: 553
USA NMDP Alaska Native or Aleut 0.2% Sample size: 1,376
USA NMDP American Indian South or Central America 0.1% Sample size: 5,926
USA NMDP Caribean Black 0.1% Sample size: 33,328
USA NMDP Caribean Indian 0.2% Sample size: 14,339
USA NMDP Chinese 6.47% Sample size: 99,672
USA NMDP European Caucasian 0,00% Sample size: 1,242,890
USA NMDP Filipino 4.21% Sample size: 50,614
USA NMDP Hawaiian or other Pacific Islander 0.81% Sample size: 11,499
USA NMDP Hispanic South or Central American 0.03% Sample size: 146,714
USA NMDP Japanese 0.06% Sample size: 24,582
USA NMDP Korean 0.34% Sample size: 77,584
USA NMDP Mexican or Chicano 0.03% Sample size: 261,235
USA NMDP Middle Eastern or North Coast of Africa 0.04% Sample size: 70,89
USA NMDP South Asian Indian 2.6% Sample size: 185,391
USA NMDP Southeast Asian 4.03% Sample size: 27,978
USA NMDP Vietnamese 13.83% Sample size: 43,54
USA North American Native 0,00% Sample size: 187
USA Philadelphia Caucasian 0,00% Sample size: 141
USA San Antonio Caucasian 0,00% Sample size: 222
USA South Texas Hispanic 0,00% Sample size: 194
Uruguay
Uzbekistan
Venezuela
Vietnam
Vietnam Hanoi Kinh 13.5% Sample size: 170
Vanuatu
Yemen
South Africa
South Africa Caucasians 0.5% Sample size: 102
South Africa Natal Tamil 3.1% Sample size: 51
South Africa Natal Zulu 0,00% Sample size: 100
Zambia
Zimbabwe
Northern Cyprus
Kosovo
Somaliland
Singapore
Singapore Chinese 5.7% Sample size: 149
Singapore Chinese Han 11.6% Sample size: 94
Singapore Javaneses 8.2% Sample size: 51
Singapore Riau Malay 8.4% Sample size: 132
Singapore Thai 6.1% Sample size: 100
Hongkong
Hong Kong Chinese 10.2% Sample size: 569
Hong Kong Chinese BMDR 9.38% Sample size: 7,595
Hong Kong Chinese cord blood registry 9.12% Sample size: 3,892